Synopsis There is a huge advancement of realizing compact and adaptable sensing instruments that combine fluidics and time-tested optical sensing mechanisms to serve a wide range of bioanalytical sensing applications. By utilizing the benefits of integrated microfluidics, the devices function on a vast array of sensing phenomena, including electrochemistry, colorimetry, chemiluminescence, and electrochemiluminescence. The focus will be on a wide variety of portable devices that can operate independently, allowing for a wide range of detection capabilities to be implemented, including biomarker analysis and environmental pollutant quantification. By implementing a cyber-physical system approach, such devices have experienced substantial enhancements in functionality, flexibility, and autonomy. Furthermore, the interdisciplinary endeavors will illustrate the potential applications of sophisticated and versatile sensing technologies. Bio Sanket Goel did BSc (H) Physics from the Ramjas College, Delhi University; MSc (Physics) from IIT Delhi; PhD (Electrical and Computer Engineering) from University of Alberta, Canada in 1998, 2000, and 2005 respectively. Since 2015, as a Professor of Electrical and Electronics Engineering Department at Hyderabad Campus of BITS Pilani, Sanket headed the Department during 2017-2020. His cross-disciplinary team encompasses several faculty members, postdocs, PhD scholars and interns. He co-founded 3 deep-tech startups, and his few technologies have been co-developed and transferred to industry. Earlier, he led the R&D department at UPES, Dehradun (2011-2015), was a PI with ASTAR, Singapore (2008- 20011), postdoc at Stanford University (2006-2008), scientist at DEBEL-DRDO (2006) and Institute of Plasma Research (2000-2001). Sanket has won several awards including IEEE India Council’s Startup of the Year Award (2024), JSPS Fellowship (2021), BITS Pilani Best Faculty Award (2021) and Fulbright fellowship (2015). Four PhD scholars have won the DBT-BIRAC GYTI awards. Currently, he is the Dean (Research and Innovation) and Head of Semiconductor CoE at BITS Pilani, Distinguished Lecturer of IEEE Sensors Council and in editorial teams of several leading journals. Co-sponsored by: IEEE Sensors Council, IEEE AP-S; IEEE MTT-S Room: SEO 1325, Bldg: Science and Engineering Offices (SEO), 851 S Morgan St, Chicago, Illinois, United States, 60607